Melanotan 2 Overdose: Health Dangers And Remedies

Having to compete for a title makes many of us willing to make sacrifices to achieve a well desired goal. Some of those sacrifices may include taking health risks to ensure we look the way we are supposed to. Bodybuilders are the most willing to try out different products, to ensure they make the best impression possible on the day of their competition. One of those products is a tan enhancing drug called melanotan 2.

Why melanotan 2 represents a health risk


Melanotan 2 has not been properly tested in any country and its list of side effects is yet to be unveiled. Some reactions have been reported, but solid research is still lacking. Various dosing charts are available all over the internet. Some of them are based on body weight, some on skin types while others take into consideration both factors. But there is no real proper way to consume this drug.

Still, every advice is followed by the statement: use a dose you feel comfortable with. This can be easily translated in “you’re on your own on this one”. You can find several guidelines and forums that abound with information. But there is no such thing as a strict rule. Just as conventional medical treatments backfire sometimes; testing new products on your own body may not lead to pleasant results.

Since proper dosing is an abstract concept, overdosing is more common than we might think. So how do you know if you got carried away with your melanotan 2 dosage? And what can you do about it? Here are a few insights.

Melanotan 2 overdose: how to recognize it:

Melanotan 2 has a different molecular structure compared to our own pigment hormones. Thus, this synthetic hormone is treated by our immune system as an invasive substance. In response, an allergic reaction will be triggered. Sometimes side effects become more severe in some individuals. That is because they either injected bacteria or impurities along with their peptide or they overdosed.

When melanotan 2 enters the body, our immune system produces antibodies that will release chemicals such as histamine and heparin into our bloodstream to fight it off. And the presence of these chemicals into our system is what produces side effects.  read more on


Now, the severity of these side effects is proportionate to the amount of melanotan 2 injected into the body. In extreme cases, users can endanger their own life, as there are susceptible to suffer from anaphylactic shock. This is a serious condition involving tissue swelling; abdominal pain; heavy breathing; vomiting; diarrhea and blood pressure fluctuations. In such cases it is best to seek medical advice or go to the emergency room as soon as possible.


Since such reactions are cause by the presence of histamine into our blood stream, it is advisable to take anti-histamine drugs 45-60 minutes prior to injecting the tanning peptide. Though side effects might still occur, they may be less severe. In any case be wary about the drugs you purchase from the pharmacy, as they come with a bag full of side effects as well.

Melanotan 2 Overdose And Skin Infections

For someone who struggles to have lean and firm muscles, being tanned is essential. This is because most bodybuilders believe that a tanned skin makes muscles look more toned. However, not everyone can tan naturally and those in this situation resort to sunbeds or unlicensed tanning drugs. Melanotan 2 is such a drug that promises buyers a natural bronzed looking skin with just a few injections. Though side effects have been reported, buyers’ demand for the drug is rising continuously.


Concerns regarding side effects

Most side effects users report are headaches, dizziness, exhaustion, vomiting, stomach pains, increased sexual drive, appearance of black spots and acne. These side effects are regarded as mild, though no one conducted any tests to see if melanotan 2 would affect human health on the long run.

Some claimed melanotan 2 made them feel extremely sick, as if they had food poisoning. Their situation was so severe; they suffered from lack of appetite and felt though the room was spinning. Some lost consciousness and were rushed to the hospital, where they confessed to using a little too much melanotan 2. Luckily, most were stabilized and further harm was prevented.


How melanotan 2 overdose affects the skin

If you really want to use a tanning drug, be very careful with dosing and take it one step at a time. It is known that melanotan 2 causes moles and freckles to darken. This draws the attention of doctors because they believe that the melanocytes forming the moles could suffer mutations and evolve into melanoma, the most aggressive type of skin cancer. There haven’t been any cases of skin cancer amongst those who used melanotan 2 tanning jab, but there have been reported other conditions.

Some buyers used tanning jabs more frequently then recommended, or injected a higher dose of melanotan 2. Some of those users were transported to medical facilities. Not only did they experience symptoms similar to food poisoning, but they also contracted skin infections. The skin infection mentioned before infection manifests itself by the appearance of blisters filled with pus that eventually pop. The skin surrounding the blister gets black and dry and eventually falls off as the blisters grow bigger.


After the blisters broke, patients were left with giant wounds that after healing would leave behind permanent scars. To counter the skin infection, patients were treated with antibiotics. In some cases it was enough to stop the infection from spreading. In others, the stage of the infection was so advanced, antibiotics proved to be only a temporary solution and patients needed to be hospitalized.

It is worth mentioning that the situations described above were isolated cases. Though no one can accuse directly the melanotan 2 tanning jabs, it is safe to take into consideration all the risks before trying new substances on our own body. We are all responsible for our well being, so when we make a choice, it could turn out to be life changing and leave us scarred for life. So making informed decisions will grant the best outcome.

Melanotan 2 Fillers And Influence Upon Health

We all know that for a bodybuilder making your muscle fibers stand out is a must. But what if what makes you look good is linked to serious health hazards? Though the matter has not been studied thoroughly, many people that have started using skin tanning drugs such as melanotan 2. They experienced side effects that sometimes led to heart and kidney problems. Some doctors go that far as to link the drug to skin cancer.


In light of recent claims, independent tests have been run on different samples of melanotan 2. To our surprise, tests have shown that melanotan 2 freeze dried powder contained more than just the active compound. The vials often contained fillers such as manniton that would make the substance look more abundant in its container.

Are fillers found in melanotan 2 flasks related to allergies?

Symptoms associated with the flu such as cough, sore throat, runny nose, dry or itchy eyes have been noticed by old and new users alike. These symptoms have been accompanied by the swelling of the area where the substance has been injected. All these symptoms can easily be pinned to allergic reactions due to impurities or solvents present in the melanotan 2 counterfeit vials.

Most suppliers guarantee a purity of 98% or 99%, but no one really knows what the other 1 or 2% is. Since the peptide is not 100% pure, one can assume that bacteria may also be found in its content. Though most bacteria die because of the binding agents or bacteriostatic water the peptide is mixed with, the resulting substance will still generate an allergic reaction. Consider this: leucocytes respond to dead viruses within vaccines. So, they will do the same when encountering dead bacteria in the blood flow.


Our natural hormone melanocortin has a linear structure, while melanotan 2 is a cyclic peptide. This means the peptide doesn’t resemble so much to our natural hormones. So, when injecting melanotan 2 into our bodies, our immune system will not recognize it and will treat it as a foreign substance. An allergic reaction will be triggered to fight off the melanotan 2.

Many health organizations claimed that mannitol is safe to consume, so why would it be linked to allergic reactions? This may be true, however mannitol is not pure either, so it may contain impurities too. Such impurities might also lead to a reaction from our immune system. In other words, we have a double source of contamination that might translate into health hazards.

What to do in case symptoms are too severe

If you experience symptoms like increased urination, nausea, vomiting or cold-like reactions, stop taking melanotan 2 immediately. Other symptoms may include: allergic skin reactions, foggy eyes, chest pain, coldness or fever, disorientation, decreased vigilance, urination trouble, acute vertigo, intense thirst or dry mouth, increased heartrate, headache, muscle pain, inflammation, or bruising at the injection area, weakness. These reactions are not common so have your peptide tested for purity and seek medical help as soon as possible.


Many allergic reactions fade away over time. Reactions may be somewhat avoided by taking antihistamine drugs prior to using melanotan 2. Keep in mind that allergic reactions may occur again if you decide to take a break or if you are in the maintenance phase and you only need to inject from time to time.

Melanotan 2 And Panic Attacks – Can They Be Related?

The desire for and acceptable physique leads many people to strange paths. Some end up abusing weight loss promoting drugs, while others are visit beauty salons all too many times. Melanotan 2 is a man-made hormone that forces the body to produce more skin pigment. This feature of melanotan 2 seems useful to treat some conditions. But without precautions, it can lead to disaster.

Melanotan 2 and panic attacks


Several years ago, a man was brought into the emergency room after taking 6 mg of melanotan 2. This is six times the recommended starting dose. His symptoms were: diffuse body aches, sweating, and a sensation of anxiety, tachycardia, and muscle tremors. This is not an isolated case. On bodybuilding forums more people claimed to have experienced anxiety. But what has been described above sounds more like a panic attack rather than anxiety attack. So what is the difference between the two and how can melanotan 2 be related to them?

Patients suffering from panic attacks experience sudden and intense symptoms. Such symptoms include: heart palpitations (tachycardia), abundant sweating, shaking, trouble breathing, chest pains, nausea or stomach pains, facial flushes and dizziness. Most panic attacks determine patients to be afraid of losing control.

On the other hand, those suffering from anxiety experience less intense symptoms. However, anxiety can last for days, weeks or even months. Main symptoms of anxiety are: muscle tension, insomnia, exhaustion, restlessness, anger, fear, increased heart rate, trouble breathing, and dizziness. Both conditions have similar symptoms, so it’s easy to confuse them.

What to do in case you have a panic attack


Panic attacks start off with intense fear. First thing that needs to be done is to disconnect from the source of the stress. Get to a safe and calm area, or ask someone you trust to take you there. Try to focus on the cause of the problem. Is the panic attack caused by present or past circumstances? Focusing on an explanation will help you put your thoughts in orders.

Try to force yourself to take regulated breaths. Practice breathing techniques. Breathe in for 2 seconds, and then breathe out for 2 seconds. Try to breathe in through the nose, and out through the mouth. Make sure to keep cool. Panic attacks are accompanied by flushing. So if you suddenly feel warm, ask someone to provide a damp cloth.

Ask for help. A key factor to overcome panic attacks is not being alone. Having a panic attack is nothing to be ashamed of. And many people want to help, though they are not sure what to do about it. Eventually, the moment of panic will pass and everything will go back to normal.

It is too early to connect melanotan 2 with panic attacks, but the case described above serves as a precedent. It’s no secret that this drug has proved to be dangerous in several cases. Warnings about the dangers that lurk around it are still vague.

An Ultimate Guide to Gonadotropin Therapy

Pulsatile secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus is available for initiation and preservation of reproductive axis of a human.

Pulsatile GnRH stimulates biosynthesis of LH (luteinizing hormone) and FSH (follicle stimulating hormone).

As a result, it can initiate the production of endogenous testosterone and spermatogenesis along with virilization and systemic secretion of testosterone. Failure of episodic GnRH secretion of gonadotropin may result in the clinical syndrome of HH (hypogonadotropic hypogonadism).


The use of AAS (anabolic androgenic steroids) may come up in a practical form of HH that is famously known as Secondary Acquired Hypogonadotropic Hypogonadism. To avoid any confusion, it is essential to understand the action of Gonadotropin therapy and selective modulators of the estrogen receptor.

Procedure of Gonadotropin Therapy

Human Chorionic Gonadotropin is effective, and its action is identical to pituitary LH. It is not affected by exogenous hormones and preexisting HPTA suppression. It may directly stimulate the dramatic increase in the production of melanotan 2 and volumes of spermatogenesis and testicular.

The basic goal of gonadotropin therapy is to restore the volume and function of testicular. The dramatic increase in testosterone is always required to avoid or reduce the unfavorable crash effect.

The majority of individuals have larger testes at baseline and HCG is sufficient to restore endogenous testosterone production at the orientation of spermatogenesis along with testicular volume.


The basic goal during the initial few weeks of PCT is to restore instantly testicular function and volume. Dramatic increase in the production of testosterone is necessary to reduce the unfavorable crash effect. HCG is sufficient to restore endogenous testosterone production, in some individuals with larger testes. Induction of spermatogenesis may cause a residual secretion of FSH.  Addition in the production of FSH is best suited for severe cases of HH, and its preparation is not available in lots of individuals.

Fasting Blood Values

SC often administers HCG (subcutaneous) or IM (intramuscular) injections. Before starting PCT, it is essential to establish blood values of baseline.

Similar principles are applied to establish values of cycle blood that are necessary to evaluate recovery. Blood work should be obtained almost four weeks after termination of PCT to determine precise readings. You have to establish the following fasting blood values:

  • Prolactin
  • Cortisol
  • LH
  • Estradiol, Extraction
  • T3 and T4, Free
  • Testosterone
  • TSH
  • Fasting Insulin
  • Somatomedin C
  • Lipid Panel
  • GGT liver value

HCG During Cycle


Nolvadex in combination with HCG should be used during prolonged and high dosage cycle. HCG ED can be combined with ED for almost 7 to 10 days successively or intermittently during the cycle. You can maintain testicular volume during the cycle to improve recovery as compared to atrophied testes and initial PCT. The solution addresses prevention of Leydig cell desensitization that is associated with the use of HCG.

To sum up, HCG is good for bodybuilders because steroids can make health worse and with the help of these injections, they can improve their health. It is essential to consult a doctor and share medical conditions.

Bits And Bobs Of HCG For Bodybuilders

These days, Bodybuilding and HCG are interrelated as Bodybuilding is now more than fun or hobby. So, men are adopting workout more seriously, and even females are getting interested in toning their physique and shaping its structure.


Moreover, as now more people are interested in this niche, physicians and doctors have proposed many different ways to improve bodybuilding experience. Hence, along with heavy workout and exercise, bodybuilders are also using many legal and illegal drugs to get better results in minimum time, HCG is one of them.

What is HCG?

Human Chorionic Gonadotropin is abbreviated as HCG– a hormone found in both male and female in a subsequent level. It is a glycoprotein that contains 237 Amino-acids with a molecular mass 2.57 kDa.

How and why Bodybuilders are using HCG?


Well, HCG is used by the bodybuilders in combo with Anabolic Steroid which is also called as anabolic androgenic steroid shortened as “AAS. When exogenous anabolic androgenic steroids are injected into the male body, the drug reacts with the body negatively and shuts down the natural production of the testosterone and prevents releasing of luteinizing hormone.

Henceforth, when the workout of bodybuilders is finished HCG is used at the end or during steroid cycles to bring the testosterone production to its natural level and to restore testicles to its original size

Along with this, HCG is also used as a low-calorie diet suitable especially for those worried about their excessive weight. Ms, Simeons, studying over pregnant women in India, negated it as a calorie deficient diet as it contains maximum 480 calories. Males and females with chubby bodies are now getting treated with the low doses of HCG drug for a slim physique.



HCG helps your body to maintain its shape in various ways such as:

  • Shrink testes to its original size
  • Helps you to avoid side effects of AAS
  • Burns off extra layers of fat
  • Help bodybuilders to get better and smooth muscles
  • Lose the weight for those who want to build their bodies to become handsome as hunks



Here are the negatives of HCG

  • Continuous HCG usage results in abnormal sperm production which is a bad sign for your health
  • Weight Lose quality is real but isn’t reliable because you have to keep your diet low to maintain the wasted level of your body.
  • To maintain weight loss, you will have to eat less than normal, and less intake of food can lead you to some serious health issues.
  • Acne in both male and female
  • Increase risk of multiple pregnancies in females
  • Cause Breast development in men
  • Tiredness in both male and female
  • Hair loss in men and women
  • Excessive fluid retention in men

Note: Due to its excessive side effects, HCG is banned by FDA to use as a diet. Anyhow if you are a bodybuilder and consuming it, try to decrease its intake amount and get proper medical checkups to avoid its side effects.

7 things to know about HCG in Bodybuilding

Eye catching body is a dream of gym lovers. They can frame their bodies quickly if they know which supplement can serve them in a better way. Professional gym owners and bodybuilders are considered a final authority in getting assistance; however, numerous of them have a different opinion about supplements to use. When you question the validity of Human Chronic Gonadotropin (HCG), experts recommend its authenticity in spite having different goals and varied workout style.


Know How to Use It

Some bodybuilders amalgamate it with a steroid to increase the production of testosterone. You can also inject it into your body with injection by adding small traces of calorie diet. A great quantity of calorie could be a cause of unnecessary fat. In a week, use its dose range from 700 to 1750 IU. Researchers and the practical outputs have verified its authenticity, so it is a safe choice. However, overdose can be harsh so evade it.

Normalizing the Testicular Function


Impaired testicular functioning damages the overall health of men. Ingestion of anabolic steroid could harm their proper functionality. HCG keeps every aspect of the body under its normal condition, and you enjoy the spice of perfect health. In addition, its use is effective at the end of an anabolic-androgenic steroid cycle to prevent the collapse of hard earned muscles. They get a much-defined look as they desired.

Post Cycle Therapy (PCT)

When you are on the workout to get strength and muscles gains, your body’s hormonal level doesn’t remain balanced. Keep the hormonal level normal; otherwise, your all efforts may go in vain. PCT protocols have emerged productive medium to sustain muscles. Along with this, utilization of Human Chorionic Gonadotropin works amazingly.



The pituitary produces HCG hormone. Being a natural analog of LH, it stimulates the sex hormone production in ovary or tests. Similar to LH, it energizes, binds and makes the functional receptors to get the desired output – testosterone production. However, while pregnancy; it is more beneficial to its counterpart LH. Later choice has some limitations.


After separating this hormone from the urine of pregnant women, this hormone is highly purified and processed with the extensive care to get the best quality. However, in the market, try to figure out the genuine pharmaceutical brands of HCG otherwise you have to experience inconveniences. It is generally available in the form of lyophilized powder, typically at 5000 or 10,000 IU per vial.


Recombinant DNA Technology and Urine Base HCG

As HGH is manufactured, similarly, it can be produced by the recombinant DNA technology. You can avail it in the form of preloaded syringes. But, the bitter fact is, it hasn’t produced enthusiastic results.

The source of urine-based HCG in the bloodstream during pregnancy contains numerous subunits in the form of monomers that prove to be more effective.


Before its usage, you have to take into consideration all aspects. Consultation with the doctor about its usage is a logical move. Some people have been the prey of acne, hair loss, tiredness, excessive fluid retention and breast development in men due to the usage of HCG.

6 Facts of HCG Bodybuilders should know about

Developing and maintaining the muscles mass is not an automatic process for the bodybuilders. They have to use various techniques to develop and maintain muscles in a specific figure. The techniques may involve a diet plan, injections, supplements and of course regular exercising. Use of Human Chorionic Gonadotropin has also become a good idea for muscles builders. In fact, HCG is a medical drug which is used to treat any disease or problem in a body. But there are also non-medical uses of it. Bodybuilders use HCG to increase their muscles mass through a proper plan with exercise under a best medical and body instructor. Here is a complete explanation about what are the HCG side effects can be expected during bodybuilding? To know about HCG, first make your mind clear by understanding the function of HCG:


What is the HCG Function for Bodybuilders

HCG stands for Human Chorionic Gonadotropin. It is a hormone, which works for testosterone levels for bodybuilders. Balanced Testosterone levels are necessary to increase muscles mass and energy. These hormones development is the continuing process of aging. However, injecting these hormones artificially for bodybuilders becomes a trend. For the muscles gain its use is accompanied with anabolic androgenic steroids.

Body Types Are Different – Know the Facts

Natural production of hormones in a body does not pilot to any side effect unless it is come up to the balance level. Any artificial or extra intake of food or medicine may create certain unwanted issues in the body. There are some side effects which may cause of using HCG for bodybuilders:


  1. It may lead to some allergic irritation, shortness of breath, throat issues, fatigue,
  2. It can increase the blood thickness in the body which tend to produce the blood clot. The thickness of blood causes a headache, redness and swelling in arm or leg.
  3. It can cause many hormonal issues which can be a reason of glands in the body.
  4. For women, the use of HCG for bodybuilding purpose can cause the fertility issues. So the use of HCG should be immediately stopped if she finds herself pregnant. It may also be a root of multiple births which is considered high-risk pregnancy.
  5. The ovarian Hyperstimulation disease in a woman can also be a cause of HCG use. The symptoms of this problem are pelvic soreness, difficulty in breathing, less urination or nausea.
  6. Another complication related to Human Chorionic Gonadotropin is Gynecomastia. It is the abnormal augmentation of the breast in men. It results because the use of HCG converts testosterone into estrogens. Estrogens are the hormones which play a role in the development of female features.
  7. image_20161004_064414_10

The use of HCG is not much sensitive, but these are the some complications which should never be ignored by the body builders. They must search well about the HCG plan, precautions, and side effects. Under a senior doctor and practitioner, it can be implemented successfully.

This article will help you to discover the HCG side effects during implementing HCG plan. If anyone found more to these, the comment box is below to share with us.